Born in 1956, Florence graduated from the Ecole Nationale des Arts Décoratifs specializing in engraving. She began her professional career as a model maker for the press, exhibiting drawings and engravings. In 1991, she directed her first short film Hammam. Since then, she has imposed a very personal style in animated cinema. She makes her films using paint, pastel or sand, directly under the camera using overlapping techniques.
Her work is noticed in different festivals in France and internationally.
She notably received the César for best short film in 2002 for On the First Sunday in August, a special mention at the Cannes Film Festival in 2006 for Conte de Quartier and received an Honorary Crystal in 2015, on the occasion of the 39th Festival Annecy International Animation Film Festival for all of his work.